What does this research mean for the field?

Among the four existing methods for assessing drug-related anticholinergic activity to reduce adverse events in the elderly, only one is clinically useful, and no single ideal evidence-based approach currently exists. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

October 18, 2005Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Methods for Assessing Drug‐Related Anticholinergic Activity

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Population

Geriatric population taking prescription and over-the-counter drugs

Design

Review

Authors

KRKelly M. RuddOklahoma State University Medical Center CRCynthia L. RaehlUNSW Sydney CBChristopher BondNorthwestern University

Discussion

Member takes

Implication

Only one anticholinergic assessment method has clinical utility in elderly patients; leaves open validation of research tools before broader adoption.

Structured PICO

Population

Geriatric population taking prescription and over-the-counter drugs

Intervention

Methods for assessing drug-related anticholinergic activity

This review identifies four methods for assessing anticholinergic drug burden in the elderly, highlighting that only one is currently clinically useful.

Limitations

No ideal evidence-based approach used

Cite This Study

Rudd et al. (2005) studied this question.

synapsesocial.com/papers/6a1889c33ad5dee7381eec2b https://doi.org/10.1592/phco.2005.25.11.1592

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Implication

Only one anticholinergic assessment method has clinical utility in elderly patients; leaves open validation of research tools before broader adoption.

Methods for Assessing Drug‐Related Anticholinergic Activity

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Methods for Assessing Drug‐Related Anticholinergic Activity

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider