What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Isolated systolic hypertension (n=4634). Primary outcome: Prevalence of isolated systolic hypertension (95% CI 14.88-16.96).

September 27, 2022BMC Cardiovascular DisordersOpen Access

Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study

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Key result

Isolated systolic hypertension affects ~16% of middle-aged and older Iranians, linked to age, BMI, and diabetes.

95% CI 14.88-16.96
n=4,634

Why the study?

Isolated systolic hypertension prevalence and related risk factors are not well known in many developing countries, including Iran.

Population

5190 people aged 40 to 70 years in Iran

Design

Population-based cohort study second phase cross-sectional analysis

Authors

AHAli HosseinzadehUniversity of British Columbia HEHossein EbrahimiIslamic Azad University, Tehran AKAhmad KhosraviShahroud University of Medical Sciences

Discussion

Member takes

Implication

Highlights ISH burden in middle-aged and older Iranians; cross-sectional data leave open causality and practice implications.

Study Design

Type

Cross-Sectional (n=4,634)

Multicenter

Yes

Structured PICO

Population

5,190 people aged 40 to 70 years from the Shahroud eye cohort study (ShECS) in Iran.

Outcome

Prevalence of isolated systolic hypertension (ISH) and associated risk factors

Isolated systolic hypertension is highly prevalent (15.89%) among middle-aged and older adults in Iran, with significant associations with age, obesity, and diabetes.

Limitations

Cross-sectional design cannot establish causal association
Did not collect data on alcohol intake, salt intake, and physical activity
Some ISH cases may be missed due to antihypertensive medications
Blood pressure was measured in one arm during a single office visit

Cite This Study

Hosseinzadeh et al. (2022) conducted a cross-sectional in Isolated systolic hypertension (n=4,634). Isolated systolic hypertension had an overall prevalence of 15.89% in the Iranian middle-aged and older population, with age, BMI, diabetes, and waist-to-hip ratio significantly increasing the odds.

synapsesocial.com/papers/6a1893780048a5c8b24aa0cd https://doi.org/10.1186/s12872-022-02856-7

Topics

Hypertension management

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Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Topics

Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider