Key Points
- To determine the duration of acute ischemic neurologic deficits and calculate the probability of spontaneous recovery over time.
- Retrospective analysis of 1,343 hospitalized patients in the Cornell Neurology Database with final diagnoses of transient ischemic attack (TIA), reversible ischemic neurologic deficit (RIND), or ischemic stroke.
- Evaluated the time to symptom resolution and quantified hourly spontaneous resolution rates at 30, 60, 90, and 120 minutes after deficit onset.
- Deficits resolved within 24 hours in 28.4% of patients (382/1,343) and between 1 and 7 days in 2.5% (34/1,343).
- Among the 382 patients with classic TIAs, symptoms resolved within 30 minutes in 50.0% (n=191) and between 30 and 60 minutes in 9.7% (n=37).
- For deficits persisting at least 60 minutes (n=1,115), only 13.8% (n=154) resolved within 24 hours, with spontaneous resolution in the subsequent hour dropping to 3.4% at 30 minutes (39/1,152), 1.9% at 60 minutes (21/1,115), 1.7% at 90 minutes (19/1,113), and 1.5% at 120 minutes (16/1,094).
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Discussion
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Implication
Database study reveals low spontaneous resolution rates in hospitalized stroke and TIA patients, indicating that deficits lasting over one hour rarely reverse quickly.
Cite This Study
David T. Levy (1988) studied this question.