Why the study?
Does ivabradine treatment increase the risk of incident atrial fibrillation?
Meta-Analysis (n=21,571)
Double-blind
Does ivabradine treatment increase the risk of incident atrial fibrillation?
Effect estimate: RR 1.15 (95% CI 1.07 to 1.24)
p-value: p=0.0027
Meta-analysis reveals that ivabradine treatment significantly increases the risk of incident atrial fibrillation, indicating it is a more common side effect than previously reported in product literature.
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Duong et al. (2021) reported a meta-analysis. Ivabradine vs. Control was evaluated on Incident atrial fibrillation during the follow-up period (RR 1.15, 95% CI 1.07 to 1.24, p=0.0027).
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