What does this research mean for the field?

During the disassembly and assembly of myofibrils in cardiac myocytes, original myofibrils form transitory polygons composed of muscle-specific proteins, while new myofibrils assemble with their distal tips terminating in adhesion plaques that act as initiating sites for new sarcomeres, analogous to in vivo intercalated discs. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 1989The Journal of Cell BiologyOpen Access

Polygons and adhesion plaques and the disassembly and assembly of myofibrils in cardiac myocytes.

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Authors

ZLZ X LinUniversity City Science Center SHS. HoltzerUniversity of Pennsylvania TST SchultheissUniversity of Lübeck

Discussion

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Implication

May guide in vitro models of sarcomere dynamics; leaves open in vivo relevance to cardiac remodeling.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Lin et al. (1989) studied this question.

synapsesocial.com/papers/6a18aef1673175fe754ac728 https://doi.org/10.1083/jcb.108.6.2355

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June 1, 1989The Journal of Cell BiologyOpen Access

Polygons and adhesion plaques and the disassembly and assembly of myofibrils in cardiac myocytes.

View Full Paper

Ask AI

Bookmark

Authors

ZLZ X LinUniversity City Science Center SHS. HoltzerUniversity of Pennsylvania TST SchultheissUniversity of Lübeck

Discussion

Member takes

Implication

May guide in vitro models of sarcomere dynamics; leaves open in vivo relevance to cardiac remodeling.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Lin et al. (1989) studied this question.

synapsesocial.com/papers/6a18aef1673175fe754ac728 https://doi.org/10.1083/jcb.108.6.2355

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