Key result
This review summarizes a decade of research investigating the role of nitric oxide in mediating unexplained limb vasodilation during body heating, ischemia, exercise, and mental stress.
Why the study?
What is the role of nitric oxide in human limb vasodilation during body heating, limb ischemia, exercise, and mental stress?
What is the role of nitric oxide in human limb vasodilation during body heating, limb ischemia, exercise, and mental stress?
This review summarizes a decade of research on the physiological role of nitric oxide in human limb vasodilation during various stressors.
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Synthesizes nitric oxide's role in stress vasodilation; leaves open clinical translation and targeted interventions.
This brief review highlights human studies on the role of nitric oxide (NO) and limb vasodilation conducted at the Mayo Clinic over the last 10 years. These studies have attempted to determine whether NO is responsible for the "unexplained" limb vasodilation seen with body heating, limb ischemia, exercise, and mental stress. Our findings are placed in context with data from others, and possible future areas of study are identified.
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Joyner et al. (2003) conducted a review in Limb vasodilation. Nitric oxide was evaluated. This review summarizes a decade of research investigating the role of nitric oxide in mediating unexplained limb vasodilation during body heating, ischemia, exercise, and mental stress.
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