Key result
Randomized controlled trials remain the gold standard driving medical science advances over five decades.
Why the study?
The randomized controlled trial sits at the top of the evidence hierarchy in evidence-based medicine, motivating an overview of its design.
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Design
Overview article
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Upholds RCTs as cardiology's top evidence tier; leaves open optimal integration with real-world data sources.
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Kenneth Stanley (2007) reported a review. Randomized controlled trials have driven medical science advances over the past 50 years and sit at the top of evidence hierarchies.
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