Population
J774 and elicited mouse peritoneal macrophages loaded with cholesteryl ester within lysosomes through…
Design
Preclinical
Authors
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Does not support selective apolipoprotein roles in foam-cell cholesterol handling; leaves open apoAI efficiency for in vivo HDL studies.
In a macrophage foam cell model, apolipoproteins AI, AII, and Cs do not selectively regulate the efflux or esterification of lysosomal versus membrane cholesterol.
Mahlberg et al. (1991) studied this question.
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