December 18, 2023AllergyOpen Access

Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology

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Accumulation of senescent immune cells drives inflammaging, and altered cell metabolism sustains their non-proliferative yet highly damaging inflammatory activity.
Position paper reviews metabolic alterations in senescent macrophages, B cells, and T cells across patients with chronic asthma and chronic obstructive pulmonary disease.
Targeting metabolic pathways of immune senescence may overcome therapeutic resistance in inflamed lungs, providing novel strategies for disease prevention and healthy aging.

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Position paper reveals metabolic pathways driving immune senescence in chronic inflammatory lung diseases, highlighting novel therapeutic strategies targeting cell metabolism.

Cite This Study

Roth‐Walter et al. (2023) studied this question.

synapsesocial.com/papers/6a18f6aa899f154814be1cc9 https://doi.org/10.1111/all.15977

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Position paper reveals metabolic pathways driving immune senescence in chronic inflammatory lung diseases, highlighting novel therapeutic strategies targeting cell metabolism.

Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology

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Discussion

Implication

Cite This Study

Metabolic pathways in immune senescence and inflammaging: Novel therapeutic strategy for chronic inflammatory lung diseases. An EAACI position paper from the Task Force for Immunopharmacology

Key Points

Discussion

Implication

Cite This Study

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