Key result
Aging shifts intraventricular flow energetics by decreasing early and increasing late diastolic kinetic energy.
Why the study?
There is a need to clarify the effect of physiological variables, specifically aging, on intraventricular kinetic energy and kinetic energy dissipation or energy loss.
Aging significantly alters diastolic intraventricular flow energetics, characterized by reduced early diastolic and increased late diastolic kinetic energy, which may reflect age-related increases in ventricular stiffness.
Age adjustment needed when interpreting intraventricular kinetic energy on imaging; leaves open prospective validation of clinical relevance.
In recent years, analysis of kinetic energy (KE) and the rate of kinetic energy dissipation (KED) or energy loss (EL) within the cardiac chambers, obtained by cardiac imaging techniques, has gained increasing attention. Thus, there is a need to clarify the effect of physiological variables, specifically aging, on these energetic measures. To elucidate this aspect, we reviewed the literature on this topic. Overall, cardiac magnetic resonance and echocardiographic studies published so far indicate that aging affects the energetics of left and right intraventricular blood flow, although not all energy measures during the cardiac cycle seem to be affected by age in the same way. Current studies, however, have limitations. Additional large, multicenter investigations are needed to test the effect of physiological variables on intraventricular KE and KED/EL measures.
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Mele et al. (2023) conducted a review in Healthy aging. Aging vs. Younger age was evaluated on Intraventricular kinetic energy and energy dissipation. Aging affects the energetics of left and right intraventricular blood flow, specifically decreasing early diastolic kinetic energy and increasing late diastolic kinetic energy.
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