Key result
Post-MI LV thrombus is linked to greater late-diastolic kinetic energy drop, marking reduced apical wash-in.
Why the study?
Does 4D flow CMR-derived left ventricular kinetic energy differ in myocardial infarction patients with versus without left ventricular thrombus?
Cohort (n=108)
Single-blind
Yes
Does 4D flow CMR-derived left ventricular kinetic energy differ in myocardial infarction patients with versus without left ventricular thrombus?
Effect estimate: beta = 11.5
Absolute Event Rate: 87% vs 78%
p-value: p=0.02
4D flow CMR reveals that myocardial infarction patients with left ventricular thrombus have significantly reduced and delayed wash-in of the left ventricle, providing a novel imaging biomarker for flow stasis.
No takes yet. Share an insight, caveat, or question.
May signal higher LVT risk post-MI via reduced A-wave KE; leaves open whether 4D flow CMR aids risk stratification.
Garg et al. (2018) conducted a cohort in Myocardial Infarction with/without Left Ventricular Thrombus (n=108). Presence of Left Ventricular Thrombus vs. Myocardial infarction without Left Ventricular Thrombus was evaluated on Relative drop in A-wave kinetic energy from mid-ventricle to apex (beta = 11.5, p=0.02). Myocardial infarction patients with left ventricular thrombus had a significantly higher relative drop in distal intra-ventricular A-wave kinetic energy compared to those without thrombus (87% vs. 78%, P=0.02), indicating reduced late-diastolic wash-in.
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