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January 1, 1981Nucleic Acids ResearchOpen Access

Transcription of the β-like globin genes and pseudogenes of the goat in a cell-free system

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Authors

DLDonal S. LuseJHJoel R. HaynesDVDonald VanLeeuwen

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Overview

Cell-free system examines gene transcription of goat beta-globin family, indicating regulatory elements influence activity.

Key Points

  • This research investigates the transcription of beta-like hemoglobin genes and pseudogenes in goats to understand regulatory mechanisms.
  • Examined transcription of beta-like hemoglobin genes in a cell-free system
  • Analyzed transcription accuracy and gene activity
  • Compared transcription of natural genes with deletion mutants and pseudogenes
  • All five beta-globin genes are transcribed equally in vitro
  • Two pseudogenes and several deletion mutants show no transcription
  • Inactive genes lack an AT-rich consensus sequence near the initiation site

Cite This Study

Luse et al. (1981) studied this question.

synapsesocial.com/papers/6a1920dcc27e07dcc0d947cehttps://doi.org/10.1093/nar/9.17.4339
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