October 1, 1997Stroke

Carotid Atherosclerosis in Men With Low Levels of HDL Cholesterol

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Population

n=202 randomly selected male veterans with coronary heart disease and low levels of HDL cholesterol but…

Design

Cross-sectional

Authors

TWTimothy J WiltBoston University HBHanna E. BloomfieldGeneral / Preventive / Lipids SRSander J. RobinsBroad Institute

Discussion

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Implication

High prevalence signals substantial residual risk in CHD despite normal LDL; leaves open whether HDL-targeted strategies improve outcomes.

Structured PICO

Population

n=202 randomly selected male veterans with coronary heart disease (CHD) and low levels of HDL cholesterol but without elevated levels of LDL cholesterol or total cholesterol, participating in the VA HDL Intervention Trial.

Outcome

Prevalence of sonographically detected carotid atherosclerosis (quantified by intima-media wall thickness [IMT])surrogate

Men with coronary heart disease and low HDL cholesterol, despite normal LDL cholesterol, have a very high prevalence of carotid atherosclerosis, highlighting significant residual cardiovascular risk.

Cite This Study

Wilt et al. (1997) studied this question.

synapsesocial.com/papers/6a19232f990f10e0212652d2 https://doi.org/10.1161/01.str.28.10.1919

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Implication

High prevalence signals substantial residual risk in CHD despite normal LDL; leaves open whether HDL-targeted strategies improve outcomes.

Carotid Atherosclerosis in Men With Low Levels of HDL Cholesterol

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Carotid Atherosclerosis in Men With Low Levels of HDL Cholesterol

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider