Why the study?
Do traditional biomedical and social risk factors predict first-ever stroke independently or jointly with hypertension?
Population
129 stroke cases with two randomly selected referents per case nested within the Västerbotten Intervention…
Design
Case-control
Key result
Hypertension, diabetes, and single marital status independently predicted first-ever stroke among 129 cases and 258 referents, with significant interactions between hypertension, smoking, and diabetes.
Authors
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May inform multifactorial stroke risk assessment; extends observational evidence on interactions but leaves open need for prospective validation.
Case-Control (n=387)
Yes
Do traditional biomedical and social risk factors predict first-ever stroke independently or jointly with hypertension?
Hypertension, diabetes, and single marital status are independent predictors of first-ever stroke, with significant interactions between hypertension and smoking/diabetes, emphasizing the need for multifactorial risk prevention.
Öhgren et al. (2000) conducted a case-control in First-ever stroke (n=387). Traditional biomedical and social risk factors was evaluated on First-ever stroke event. Hypertension, diabetes, and single marital status independently predicted first-ever stroke among 129 cases and 258 referents, with significant interactions between hypertension, smoking, and diabetes.