Key result
NSTE-MINOCA links to ~157% higher major event risk versus STE-MINOCA, driven by cardiovascular rehospitalization.
Why the study?
The disparity between ST-segment elevation and non-ST-segment elevation myocardial infarction without obstructive coronary artery (STE-MINOCA and NSTE-MINOCA) was unclear.
Does NSTE-MINOCA presentation increase the risk of long-term adverse cardiovascular events compared to STE-MINOCA in patients with myocardial infarction with nonobstructive coronary arteries?
Population
107 patients diagnosed with MINOCA
Comparison
STE-MINOCA vs NSTE-MINOCA
Design
Cross-sectional study
Follow-up
Median 24.5 months
Authors
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May warrant closer surveillance for NSTE-MINOCA; extends MINOCA risk stratification data but leaves causal management implications open.
Cross-Sectional (n=107)
No
Does NSTE-MINOCA presentation increase the risk of long-term adverse cardiovascular events compared to STE-MINOCA in patients with myocardial infarction with nonobstructive coronary arteries?
Effect estimate: HR 2.57 (95% CI 1.10-6.02)
Absolute Event Rate: 37% vs 20.6%
p-value: p=0.030
In patients with MINOCA, an NSTE presentation is associated with a significantly higher long-term risk of cardiovascular-related rehospitalization compared to an STE presentation.
Li et al. (2022) conducted a cross-sectional in Myocardial infarction without obstructive coronary artery (MINOCA) (n=107). NSTE-MINOCA vs. STE-MINOCA was evaluated on Long-term composite events (all-cause mortality, heart failure, recurrence of AMI, cardiovascular-related rehospitalization, and stroke) (HR 2.57, 95% CI 1.10-6.02, p=0.030). NSTE-MINOCA was associated with an increased risk of long-term composite cardiovascular events compared to STE-MINOCA (HR 2.57), primarily driven by cardiovascular-related rehospitalization.
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