Genetic analysis of SARS-CoV-2 XFG lineage finds low variability, indicating lineage turnover influences prevalence.
subs/site/year) was comparable to those of its parental lineages, supporting a relatively low level of genetic variability. Overall, these findings suggest that the widespread prevalence of XFG is more likely driven by lineage turnover rather than increased transmissibility, highlighting the importance of continuous genomic surveillance for monitoring emerging SARS-CoV-2 lineages.
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Deplano et al. (2026) studied this question.
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