What does this research mean for the field?

In infants aged 28 to 90 days suspected of sepsis, high procalcitonin levels are significantly associated with positive urinary cultures but do not predict positive blood or cerebrospinal fluid cultures. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to evaluate the association between high procalcitonin levels and positive cultures in infants suspected of sepsis or serious bacterial infections.

May 29, 2026Pediatric Health Medicine and TherapeuticsOpen Access

Procalcitonin for Predicting Sepsis in Infants in the Emergency Department: A Retrospective Study

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Authors

NANesrin AlharthyKing Saud bin Abdulaziz University for Health Sciences MAMohammad AlreefiNational Guard Health Affairs MAMesaed AlsenaniNational Guard Health Affairs

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Implication

Retrospective study evaluates procalcitonin's role in predicting outcomes of urinary cultures in infants, indicating clinical decision-making improvements.

Key Points

The aim is to evaluate the association between high procalcitonin levels and positive cultures in infants suspected of sepsis or serious bacterial infections.
Retrospective cross-sectional study including infants aged 28 to 90 days with simultaneous PCT, blood, urine, and CSF cultures.
Conducted from January 2020 to December 2021, analyzing 352 patients at a single center.
Statistical analyses performed using SPSS software version 27.0.1.
PCT levels did not show a significant association with blood or CSF culture outcomes.
There was a significant association between high PCT levels and positive urine cultures (p = 0.008).
Nonsignificant association found between PCT levels and respiratory viral infections.

Cite This Study

Alharthy et al. (2026) studied this question.

synapsesocial.com/papers/6a192cb4fab5b468c44157dd https://doi.org/10.2147/phmt.s589691

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Implication

Retrospective study evaluates procalcitonin's role in predicting outcomes of urinary cultures in infants, indicating clinical decision-making improvements.

Procalcitonin for Predicting Sepsis in Infants in the Emergency Department: A Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Procalcitonin for Predicting Sepsis in Infants in the Emergency Department: A Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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