A model of 3D confluent tissue behaves as an under-constrained glass

Chengling Li; Matthias Merkel; Daniel Sussman

doi:10.1039/d6sm00255b

January 1, 2026Soft MatterOpen Access

A model of 3D confluent tissue behaves as an under-constrained glass

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Key Points

This research aims to explore the behavior of 3D confluent tissue in terms of glassy dynamics.
Examined the cooling dynamics of 3D confluent tissue models
Analyzed the material's response in comparison to glassy materials
Reference to previously established 2D cell-based models
Identified slow dynamics in the model similar to glassy materials
Observed behavior consistent with both Arrhenius and super-Arrhenius dynamics
Highlighted implications for understanding biological tissue properties in terms of material science

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Implication

Reveals glassy behavior dynamics in 3D tissue models, suggesting implications for biological material studies.

Abstract

The dynamics of glassy materials slows down upon cooling, typically showing either Arrhenius or super-Arrhenius behavior. However, it was recently shown that 2D cell-based models for biological tissues can be...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a192de6fab5b468c4416df8 https://doi.org/10.1039/d6sm00255b

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A model of 3D confluent tissue behaves as an under-constrained glass

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

A model of 3D confluent tissue behaves as an under-constrained glass

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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