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This study investigates how electroacupuncture affects brain injuries caused by ischemia-reperfusion, focusing on recovery and protein expression.

Electroacupuncture Attenuates Cerebral Ischemia/Reperfusion Injury and Enhances Neurological Recovery via Modulating Ferroptosis-Associated Proteins

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This study investigates how electroacupuncture affects brain injuries caused by ischemia-reperfusion, focusing on recovery and protein expression.
Thirty-six 3-month-old male Sprague Dawley rats were randomly assigned to sham, CIRI model, and CIRI + EA groups (n=12/group).
The CIRI model was induced by left middle cerebral artery occlusion, with the EA group receiving daily stimulation for 5 days.
Neurological function, serum cytokine levels, infarct volume, histopathology, and protein/mRNA expression were evaluated.
EA treatment significantly reduced serum TNF-α and IL-6 levels.
The EA group showed improved limb motor function and decreased Longa scores compared to the CIRI model group.
EA therapy notably reduced cerebral infarct volume and neuronal damage while upregulating GPX4 and downregulating ACSL4 and TFRC expressions.

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Randomized trial investigates electroacupuncture's effects on neurological function in rats, indicating therapeutic potential for brain injury.

Sun et al. (2026) studied this question.

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Randomized trial investigates electroacupuncture's effects on neurological function in rats, indicating therapeutic potential for brain injury.