June 1, 1993Medical Decision Making
Stability of Time-tradeoff Utilities in Survivors of Myocardial Infarction
Why the study?
Do time-tradeoff utilities change over time and correlate with functional status in survivors of myocardial infarction?
Population
67 patients who had recently had myocardial infarction
Design
Cohort
Follow-up
up to 1.5 years (mean interval 8.4 months)
Authors
Discussion
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Member takes
Implication
Stable post-MI time-tradeoff utilities without functional correlation; leaves open their validity as longitudinal patient-reported outcomes in observational cohorts.
Key Points
- To examine if time-tradeoff utilities in myocardial infarction survivors change and whether they relate to functional status over time.
- Conducted serial interviews with 67 myocardial infarction survivors
- Measured time-tradeoff and functional status using multiple scales over 1.5 years
- Analyzed changes in scores and their correlations with health status indicators
- Mean time-tradeoff score was stable at 0.88 (95% Cl: 0.84, 0.93)
- 42% of patients improved in Karnofsky and Specific Activity Scale classes
- Rating scale scores improved by 0.06 (p < 0.002) while time-tradeoff scores showed no significant change (p = NS)
Structured PICO
Do time-tradeoff utilities change over time and correlate with functional status in survivors of myocardial infarction?
P
Population
67 patients who had recently had myocardial infarction
I
Intervention
Serial interviews using a time tradeoff and three measures of functional status
O
Outcome
Change in time-tradeoff utilities over time and correlation with changes in functional statuspatient reported
In survivors of recent myocardial infarction, time-tradeoff utilities remain stable over time and do not correlate with changes in functional status.
Cite This Study
Tsevat et al. (1993) studied this question.