Key result
1.5-T CMR mapping establishes uniform T1, T2, and ECV reference values for healthy Thai adults.
Why the study?
Data pertinent to cardiovascular magnetic resonance mapping parameters in healthy Asian populations, particularly with GE scanners, are limited.
What are the normal reference values for myocardial T1, T2, and ECV mapping using 1.5-T GE CMR in a healthy Thai population?
Cross-Sectional (n=51)
What are the normal reference values for myocardial T1, T2, and ECV mapping using 1.5-T GE CMR in a healthy Thai population?
Answers are grounded in this paper and cite their sources.
This study establishes normal reference values for myocardial T1, T2, and ECV mapping using a 1.5-T GE scanner in a healthy Thai population, providing critical baseline data for clinical CMR interpretation.
BACKGROUND: Parametric mapping is a pivotal technique in diagnostic and prognostic cardiovascular magnetic resonance (CMR). However, data pertinent to mapping parameters in healthy Asian populations, particularly with GE scanners, are limited. PURPOSE: To establish normal reference values for T1, T2, and ECV using 1.5-T GE CMR in a healthy Thai population. METHODS: Healthy volunteers undergoing orthopedic MRI with gadolinium injection were recruited. Health status was confirmed through medical history, ECG, laboratory investigations, and echocardiography. CMR scans included MOLLI for T1 mapping, MEFSE for T2 mapping, and ECV calculation. Inter- and intra-observer variation were assessed. RESULTS: Fifty-one participants were included, 18 (35.29%) were males with a mean age of 41.49 ± 15.96 years. Mean global native T1, post-contrast T1, T2, and ECV were 1037.19 ± 51.84 ms, 456.76 ± 43.98 ms, 49.93 ± 4.67 ms, and 27.06 ± 4.50%, respectively. No significant differences were observed between sexes or age group (p > 0.05). Reproducibility was classed as good to excellent (ICC ≥ 0.75) CONCLUSIONS: Reference values for T1, T2, post-contrast T1, and ECV mapping in a healthy Thai population using a 1.5-T GE scanner, were established. These findings provide critical reference data for cardiac MR examinations.
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Noparatkailas et al. (2026) conducted a cross-sectional in Healthy volunteers (n=51). 1.5-T GE CMR mapping was evaluated on Normal reference values for T1, T2, post-contrast T1, and ECV. In a healthy Thai population, 1.5-T GE CMR mapping established mean global native T1 of 1037.19 ms, T2 of 49.93 ms, and ECV of 27.06%, with no significant differences between sexes or age groups.
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