What question did this study set out to answer?

This study aims to identify indocyanine green fluorescence parameters that can predict intraoperative hypoperfusion during colorectal cancer surgery.

Decreased fluorescence latency and plateau intensity ratio as predictive markers of intraoperative hypoperfusion: quantitative indocyanine green perfusion analysis in colorectal cancer surgery

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Randomized trial identifies latency and plateau intensity ratio predicting hypoperfusion, suggesting improved surgical outcomes.

This study aims to identify indocyanine green fluorescence parameters that can predict intraoperative hypoperfusion during colorectal cancer surgery.
Analyzed 80 patients undergoing colorectal cancer resection from 2018 to 2022.
Evaluated intraoperative perfusion through near-infrared indocyanine green angiography and post hoc fluorescence time-intensity curves.
Assessed associations with hypoperfusion using group comparisons and receiver operating characteristic (ROC) analysis.
Shorter latency in hypoperfused cases (5.5 seconds vs. 20.0 seconds; P=0.003).
Decreased plateau intensity ratio in hypoperfused cases (0.6 vs. 0.8; P=0.045).
Latency demonstrated good diagnostic performance (AUC 0.76; sensitivity 33.3%, specificity 92.8%).

Daniluk-Marsy et al. (2026) studied this question.

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