Key result
Prospective cohort evaluates correlation between ECG criteria and echocardiographic LA volume and function.
Why the study?
Current electrocardiographic criteria for left atrial abnormality have high specificity but low sensitivity, and P-wave terminal force in V1 varies with electrode placement.
Do ECG criteria for left atrial abnormality correlate with left atrial volume and function assessed by speckle tracking echocardiography?
Cohort
Single-blind
No
Do ECG criteria for left atrial abnormality correlate with left atrial volume and function assessed by speckle tracking echocardiography?
Answers are grounded in this paper and cite their sources.
Protocol for prospective cohort to refine ECG left atrial abnormality criteria; leaves open correlation with speckle tracking echocardiography parameters.
Background The criteria applied for diagnosis of left atrial (LA) abnormality using electrocardiogram (ECG) have high specificity but low sensitivity. In fact, some authors have suggested classifying P‐wave anomalies associated with LA abnormality and interatrial block as “atrial abnormalities.” The most widely known ECG criteria for LA abnormality include P‐wave duration, morphology and voltage of P wave in inferior leads, presence of P‐wave terminal force in V 1 (PtfV 1 ), and P‐wave axis and area. PtfV 1 has also been reported to vary according to misplacement of the V 1 and V 2 electrodes. Methods The objective of this observational cohort study is to determine the degree of correlation between ECG criteria for LA abnormality and left atrium volume and functionality, as determined by speckle tracking echocardiography. The study also aims to investigate the correlation between these echocardiographic parameters and PtfV 1 value by placing the V 1 and V 2 electrodes in the second, third, and fourth intercostal spaces. Results and Conclusions Our results could help to clarify whether the decrease in left atrial deformity, which is currently considered a surrogate target of fibrosis, correlates better with ECG criteria for LA abnormality than atrial volumes.
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Lacalzada‐Almeida et al. (2020) conducted a cohort in Left atrial abnormality. ECG criteria for left atrial abnormality vs. Echocardiographic parameters (LAV max and STE) was evaluated on Correlation between ECG criteria for LA abnormality and left atrium volume and functionality. This is a study design paper describing a prospective observational cohort study to evaluate the correlation between ECG criteria for left atrial abnormality and echocardiographic parameters; no results are reported.
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