Why the study?
Do electrocardiographic criteria accurately predict left atrial enlargement compared to echocardiography in patients in sinus rhythm?
Do electrocardiographic criteria accurately predict left atrial enlargement compared to echocardiography in patients in sinus rhythm?
Changes in P wave morphology on electrocardiogram serve as a reasonably specific but less sensitive indicator of left atrial enlargement when compared to echocardiography.
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ECG criteria show moderate accuracy for left atrial enlargement; leaves open whether they can guide decisions without echocardiography.
A comparison of electrocardiographic manifestations of left atrial enlargement (LAE) and left atrial size by echocardiography was made in 307 patients in sinus rhythm. Electrocardiographic criteria used were L:P wave duration in lead II equal to or greater than 0.12 sec; Va: the ratio of the duration of negative terminal P in V1 to the P-R segment equal to or greater than 1.0; Vb: a negative P terminal force in V1 less than -0.03 mm sec. The echocardiographic diagnosis of left atrial enlargement was based on 1) transverse dimension greater than 4.0 cm; or 2) a ratio of transverse atrial to transverse aortic root dimension greater than 1.17. In the presence of left atrial enlargement, a combination of criteria occurred more often than a single criterion. The overall predictive index of the electrocardiogram for left atrial enlargement was 63% (excluding criterion Vb raised probability to 80%); and that for absence of left atrial enlargement was 78%. The index of coarse versus fine fibrillary waves was unreliable in predicting left atrial enlargement. Changes in P wave morphology may be used as a reasonably specific but less sensitive indicator of left atrial enlargement.
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Waggoner et al. (1976) studied this question.
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