Each 10% increase in relative aerobic workload increased all-cause mortality by 13% and CHD mortality by 28% (P<0.01), and leisure time physical activity increased mortality risks in men with CHD.
Cohort (n=1,891)
Do occupational and leisure time physical activity affect 22-year all-cause and coronary heart disease mortality in men?
Occupational physical activity is positively associated with mortality, and leisure time physical activity increases mortality risks specifically in men with pre-existing CHD, challenging conventional views on exercise in this population.
Effect estimate: 13% increase (all-cause) and 28% increase (CHD) per 10% relative aerobic workload
p-value: p=<0.01
BACKGROUND: This study explores the effects of occupational (OPA) and leisure time physical activity (LTPA) on mortality relative to cardiorespiratory fitness and pre-existing coronary heart disease (CHD). METHODS: max), LTPA, and 22-year mortality among 1891 Finnish men were assessed by Cox regression models stratified by CHD and adjusted for 19 confounders. RESULTS: In fully adjusted models, each 10% of relative aerobic workload increased all-cause mortality by 13% and CHD mortality 28% (P < 0.01). Compared to healthy subjects, men with CHD experienced lower mortality risks due to OPA and higher risks due to LTPA. While LTPA had no effect among healthy men, in men with CHD each weekly hour of conditioning LTPA increased all-cause mortality risks by 10% and CHD mortality by14%. CONCLUSION: OPA was positively associated with both all-cause and CHD mortality. LTPA was not protective. Among men with CHD, LTPA increased mortality risks.
Krause et al. (Wed,) conducted a cohort in Coronary heart disease (CHD) and healthy subjects (n=1,891). Occupational and leisure time physical activity was evaluated on All-cause and coronary heart disease mortality (13% increase (all-cause) and 28% increase (CHD) per 10% relative aerobic workload, p=<0.01). Each 10% increase in relative aerobic workload increased all-cause mortality by 13% and CHD mortality by 28% (P<0.01), and leisure time physical activity increased mortality risks in men with CHD.