What question did this study set out to answer?

This research aims to investigate the link between leisure time physical activity (LTPA) and mortality risks associated with coronary heart disease (CHD) and all causes over 16 years.

July 1, 1997International Journal of Sports Medicine

Leisure Time Physical Activity and the 16-Year Risks of Mortality from Coronary Heart Disease and All-Causes in the Multiple Risk Factor Intervention Trial (MRFIT)

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Why the study?

Does leisure time physical activity reduce the risk of death from coronary heart disease and all-causes in middle-aged men at high risk for CHD?

Population

12,138 middle-aged men at high risk for coronary heart disease participating in the Multiple Risk Factor…

Comparison

Higher levels of leisure time physical activity… vs Least-active decile of LTPA averaging 4.9 min/d

Design

Cohort

Follow-up

16-year

Authors

ALA. S. LeonPennington Biomedical Research Center MMM J MyersSt. Catherine University JCJohn E. ConnettUniversity of Minnesota

Discussion

Member takes

Implication

Modest LTPA linked to lower mortality in high-risk men; leaves open causality and practice change pending RCTs.

Key Points

This research aims to investigate the link between leisure time physical activity (LTPA) and mortality risks associated with coronary heart disease (CHD) and all causes over 16 years.
Prospective study involving 12,138 middle-aged men at high risk for CHD from the MRFIT.
Men classified into deciles based on average minutes per day of LTPA reported at baseline.
Cumulative CHD and all-cause mortality rates assessed at a 16-year follow-up.
Men in the least-active decile (4.9 min/d LTPA) had 29% higher mortality for CHD and 22% for all causes compared to those averaging 22.7 min/d.
Significant mortality reduction found with 10 to 36 min/d of moderate intensity LTPA for preventing premature mortality from CHD.
The associations remained significant after accounting for confounding factors (P < 0.05).

Structured PICO

Does leisure time physical activity reduce the risk of death from coronary heart disease and all-causes in middle-aged men at high risk for CHD?

Population

12,138 middle-aged men at high risk for coronary heart disease (CHD) participating in the Multiple Risk Factor Intervention Trial (MRFIT)

Intervention

Higher levels of leisure time physical activity (LTPA), specifically deciles 2 to 4 averaging 22.7 min/d of predominantly light and moderate LTPA (range 10-36 min/d)

Comparator

Least-active decile of LTPA averaging 4.9 min/d (range 0 to .9 min/d)

Outcome

Cumulative death from coronary heart disease (CHD) and all-causes at 16-year follow-uphard clinical

A relatively small amount (10 to 36 min/d) of daily moderate intensity leisure time physical activity is associated with significantly reduced premature mortality from CHD and all-causes in high-risk middle-aged men.

Cite This Study

Leon et al. (1997) studied this question.

synapsesocial.com/papers/69f6922cc2e2af49314407b4 https://doi.org/10.1055/s-2007-972717

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Leisure Time Physical Activity and the 16-Year Risks of Mortality from Coronary Heart Disease and All-Causes in the Multiple Risk Factor Intervention Trial (MRFIT)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Leisure Time Physical Activity and the 16-Year Risks of Mortality from Coronary Heart Disease and All-Causes in the Multiple Risk Factor Intervention Trial (MRFIT)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider