Key result
Age-standardized CVD mortality drops ~19% across BRICS-Plus countries despite rising total deaths.
Why the study?
The authors sought to explore epidemiological trends in cardiovascular disease mortality attributable to modifiable risk factors and associations with sociodemographic index across 35 BRICS-Plus countries.
Observational
Effect estimate: -19.3%
Absolute Event Rate: 296% vs 367%
Despite reductions in age-standardized CVD mortality rates across BRICS-Plus countries, absolute CVD deaths have nearly doubled from 1990 to 2019, driven by population growth, aging, and a concerning rise in BMI-related mortality among younger adults.
Population growth and aging may offset rate gains in BRICS-Plus; leaves open whether rising BMI will reverse progress.
BRICS-Plus countries (Brazil, Russia, India, China, South Africa, and 30 other countries) is a group of 35 countries with emerging economies making up more than half of the world's population. We explored epidemiological trends of cardiovascular disease (CVD) mortality attributable to modifiable risk factors and its association with period and birth cohort effects and sociodemographic index (SDI) across BRICS-Plus countries by using joinpoint regression and age-period-cohort modeling from 1990 to 2019. Between 1990 and 2019, the all-ages CVD deaths increased by 85.2% (6.1 million to 11.3 million) across BRICS-Plus countries. The CVD age-standardized mortality rate attributable to dietary risks and smoking significantly decreased across BRICS-Plus countries, with some exceptions. However, four-fifths of BRICS-Plus countries observed a remarkable increasing trend of high body mass-index (BMI)-related CVD deaths, in particular, among younger adults (25-49 years). Early birth cohorts and individuals aged greater than 50 years showed a higher risk of CVD mortality. Both the China-ASEAN FTA and Mercosur regions stand out for their successful sociodemographic transition, with a significant reduction in CVD mortality over the study period. Singapore and Brazil achieved great progress in CVD mortality reduction and the other BRICS-Plus countries should follow their lead in adopting public health policies and initiatives into practice.
No takes yet. Share an insight, caveat, or question.
Nawsherwan et al. (2023) conducted an observational in Cardiovascular disease mortality. Modifiable risk factors (dietary risks, high BMI, smoking) vs. 1990 baseline was evaluated on Age-standardized mortality rate (ASMR) of cardiovascular disease per 100,000 (-19.3%). Between 1990 and 2019, all-ages cardiovascular disease deaths increased by 85.2% across BRICS-Plus countries, while the age-standardized mortality rate decreased by 19.3%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: