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There is a gap in the reticulin at the glomerular root of the mammalian kidney. This gap leaves the macular segment of the second convoluted tubule in intimate contact with the arteriolar cells, which in this region contain granules consisting of or containing masked lipoid. Methods are given for the demonstration of these granules in the mouse, rabbit, and man. The cells of the macula densa of the mouse are poor in lipoid, and there is thus a striking contrast both with the adjoining cells of the same tubule and with the adjacent arteriolar cells.
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J. F. A. McManus (1947) studied this question.
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