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Assay development study reveals specific quantification of somatomedin-C in serum samples, highlighting improved diagnostic accuracy for pituitary disorders.
A C T The development of a radioimmunoassay for somatomedin-C has for the first time made it possible to discriminate between serum concentrations of a single peptide or closely related group of peptides and the net somatomedin activity measured by less specific bioassay and radioreceptor techniques. Anti- bodies to human somatomedin-C were raised in rabbits using a somatomedin-C ovalbumin complex as the anti- gen. A variety of peptide hormones at concentrations up to 1 ,uM are not recognized by the antibody.
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Furlanetto et al. (1977) studied this question.
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