What question did this study set out to answer?

This analysis investigates whether gender influences the treatment of patients with acute myocardial infarction during hospitalization and follow-up.

November 19, 2008Cardiology

Treatment of Patients with Acute Myocardial Infarction in Relation to Gender

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Why the study?

Are there gender differences in pharmacological treatments and revascularization procedures for patients with acute myocardial infarction?

Population

921 patients who suffered an acute myocardial infarction in 1986 or 1987 at a single hospital

Comparison

Female gender (observational comparison) vs Male gender

Design

Cohort

Follow-up

1 year

Authors

BKBj ouml rn W. KarlsonSahlgrenska University Hospital MHMarianne HartfordUniversity of Gothenburg JHJohan HerlitzGeneral Cardiology

Discussion

Member takes

Implication

Minor sex differences in AMI pharmacotherapy were non-prognostic; leaves open whether equity holds in contemporary reperfusion eras.

Key Points

This analysis investigates whether gender influences the treatment of patients with acute myocardial infarction during hospitalization and follow-up.
Compared treatments during hospitalization and 1 year follow-up in 300 women and 621 men (1986-1987)
Analyzed morphine dosage, anticoagulant prescriptions, and revascularization procedures
Examined treatment patterns before thrombolytic therapy became routine.
Men received a higher mean dose of morphine during the first 3 days (14.5 vs. 9.8 mg, p < 0.001)
More men were given morphine after 24 hours (65.4% vs. 49.0%, p < 0.01) and prescribed anticoagulants at discharge (18% vs. 12%, p < 0.05)
After 1 year, more women were on diuretics (61.3% vs. 42.8%, p < 0.001), but no major differences in revascularization procedures were found.

Structured PICO

Are there gender differences in pharmacological treatments and revascularization procedures for patients with acute myocardial infarction?

Population

921 patients (300 women and 621 men) who suffered an acute myocardial infarction (AMI) in 1986 or 1987 at a single hospital

Intervention

Female gender (observational comparison)

Comparator

Male gender

Outcome

Pharmacological treatments and revascularization procedures during hospitalization and 1 year of follow-up

In the pre-thrombolytic era, there were minor differences in pharmacological therapy between men and women with AMI, but no major differences in revascularization or treatments affecting prognosis.

Limitations

Performed before thrombolytic therapy was routinely used

Cite This Study

Karlson et al. (2008) studied this question.

synapsesocial.com/papers/6a194fef0b4377da6557f34e https://doi.org/10.1159/000177092

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Treatment of Patients with Acute Myocardial Infarction in Relation to Gender

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Treatment of Patients with Acute Myocardial Infarction in Relation to Gender

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider