Population
Escherichia coli expressing a 25 kDa fragment of beta-type troponin T (beta-TnT) from rabbit skeletal muscle
Comparison
Expressed beta-TnT fragment vs Authentic full-length alpha-TnT
Design
Preclinical
Authors
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Truncated beta-TnT regulates ATPase equivalently in animal models; leaves open N-terminal domain necessity in human cardiac troponin.
Deletion of the variable N-terminal region and alteration of the sequence type to beta-type do not significantly affect the regulatory action of troponin T on actomyosin ATPase.
Fujita et al. (1992) studied this question.
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