Not all senile dementias are irreversible. As this--the first in a series of articles stressing the importance of the early detection of disease states--points out, dementia has been shown to be secondary to treatable disorders in more than 20% of these patients. Investigative efforts, from primary screening to painstaking differential diagnostic approaches, can identify remediable or controllable causes.
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Robert Katzman (1981) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: