What does this research mean for the field?

A 15-week exercise training program significantly improves cardiopulmonary function and overall quality of life in postmenopausal breast cancer survivors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 29, 2003Journal of Clinical Oncology

Randomized Controlled Trial of Exercise Training in Postmenopausal Breast Cancer Survivors: Cardiopulmonary and Quality of Life Outcomes

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Why the study?

Does exercise training improve cardiopulmonary function and quality of life in postmenopausal breast cancer survivors?

Key Points

To determine the effects of cycle ergometer exercise training on cardiopulmonary function and quality of life in postmenopausal breast cancer survivors who completed primary cancer therapy.
Fifty-three postmenopausal breast cancer survivors were randomly assigned to an exercise group (n = 25) or a non-training control group (n = 28).
The exercise group trained on cycle ergometers 3 times per week for 15 weeks at an intensity targeting the ventilatory equivalent for carbon dioxide.
Primary endpoints were changes in peak oxygen consumption evaluated via graded gas exchange testing and quality of life measured with the Functional Assessment of Cancer Therapy-Breast scale.
Peak oxygen consumption increased by 0.24 L/min with exercise and decreased by 0.05 L/min in controls (mean difference: 0.29 L/min; 95% CI, 0.18 to 0.40; P < .001).
Overall quality of life increased by 9.1 points in the exercise group compared with 0.3 points in controls (mean difference: 8.8 points; 95% CI, 3.6 to 14.0; P = .001).
Changes in peak oxygen consumption positively correlated with improvements in overall quality of life (r = 0.45; P < .01), with 52 participants completing the trial.

Structured PICO

Does exercise training improve cardiopulmonary function and quality of life in postmenopausal breast cancer survivors?

Population

53 postmenopausal breast cancer survivors who had completed surgery, radiotherapy, and/or chemotherapy with or without current hormone therapy use.

Intervention

Exercise training on cycle ergometers 3 times per week for 15 weeks at a power output that elicited the ventilatory equivalent for carbon dioxide.

Comparator

Control group that did not undergo exercise training.

Outcome

Changes in peak oxygen consumption (assessed by graded exercise test) and overall quality of life (assessed by Functional Assessment of Cancer Therapy-Breast scale) from baseline to postintervention (15 weeks).patient reported

A 15-week exercise training program significantly improves cardiopulmonary fitness and quality of life in postmenopausal breast cancer survivors.

Discussion

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Implication

Supports exercise referral in postmenopausal breast cancer survivors; confirms cardiopulmonary and QOL benefits in RCT.

Cite This Study

Courneya et al. (2003) studied this question.

synapsesocial.com/papers/6a1965d7dec6c1694ed97da7 https://doi.org/10.1200/jco.2003.04.093

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Randomized Controlled Trial of Exercise Training in Postmenopausal Breast Cancer Survivors: Cardiopulmonary and Quality of Life Outcomes

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Randomized Controlled Trial of Exercise Training in Postmenopausal Breast Cancer Survivors: Cardiopulmonary and Quality of Life Outcomes

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

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