November 1, 2006Psychological Medicine
Clinically defined vascular depression in the general population
Why the study?
Do subjects with vascular risk factors exhibit a specific symptom profile of vascular depression compared to those without?
Population
Subjects with and without vascular risk factors from two large Dutch community-based studies
Comparison
Presence of vascular risk factors vs Absence of vascular risk factors
Design
Cohort
Authors
Discussion
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Member takes
Implication
Does not support a distinct symptom profile for vascular depression; leaves open the validity of this subtype in general populations.
Structured PICO
Do subjects with vascular risk factors exhibit a specific symptom profile of vascular depression compared to those without?
P
Population
Subjects with and without vascular risk factors from two large Dutch community-based studies (the Rotterdam Study and the Amsterdam Study of the Elderly [AMSTEL])
I
Intervention
Presence of vascular risk factors
C
Comparator
Absence of vascular risk factors
O
Outcome
Symptom profile of depression (including psychomotor retardation, anhedonia, loss of energy, and physical disability)patient reported
There is no evidence for a specific symptom profile of vascular depression in the general population, challenging the concept of a clinically distinct vascular depression subtype.
Cite This Study
Naarding et al. (2006) studied this question.