What does this research mean for the field?

Venous thromboembolism is highly prevalent in brain tumor patients, and while therapeutic anticoagulation with low-molecular-weight heparin is safe and effective for established VTE, routine thromboprophylaxis and novel oral anticoagulants are not currently recommended. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

March 5, 2014Seminars in Thrombosis and Hemostasis

Thrombosis in Brain Tumors

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Population

Patients with brain tumors at risk for or with established venous thromboembolism

Design

Review

Authors

JJJasmin JoBrigham and Women's Hospital DSDavid SchiffChicago Department of Public Health JPJames PerryOntario Institute for Cancer Research

Discussion

Member takes

Implication

Anticoagulation appropriate for established VTE in brain tumor patients; leaves open prophylaxis efficacy pending prospective trials.

Structured PICO

Population

Patients with brain tumors (including high-grade glioma, brain metastasis, and primary CNS lymphoma) at risk for or with established venous thromboembolism (VTE)

Intervention

Anticoagulation therapy (unfractionated heparin, low-molecular-weight heparin, warfarin, and novel oral anticoagulants)

Therapeutic anticoagulation is safe and effective for established VTE in brain tumor patients, but routine primary thromboprophylaxis is not recommended.

Cite This Study

Jo et al. (2014) studied this question.

synapsesocial.com/papers/6a197d2ddec6c1694ed99d44 https://doi.org/10.1055/s-0034-1370791

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Thrombosis in Brain Tumors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Thrombosis in Brain Tumors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider