Population
Bovine pulmonary arterial circulation (conduit and resistance pulmonary arteries)
Comparison
Immunoblotting and immunohistochemistry vs Comparison between conduit and resistance…
Design
Preclinical
Authors
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May implicate Kv β-subunits in resistance-artery hypoxic vasoconstriction; challenges alpha-subunit consensus but remains hypothesis-generating in animals.
The dramatic increase in KV channel beta-subunits along the pulmonary arterial tree suggests they play a key role in pulmonary arterial oxygen sensing.
Coppock et al. (2001) studied this question.
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