Why the study?
Does short-term exposure to repetitive hypoxic apnoeas alter baroreflex sensitivity in humans?
Population
19 human subjects (14 in the intervention group, mean age 26 +/- 1 years; 5 in the time control group)
Comparison
Repetitive hypoxic apnoeas involving 20-second… vs Time control with no RHA
Design
Other
Follow-up
Approximately 50 minutes post-intervention
Authors
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Short-term RHA resets baroreflex operating points without altering sensitivity; hypothesis-generating for autonomic dysregulation in OSA, no practice change yet.
Does short-term exposure to repetitive hypoxic apnoeas alter baroreflex sensitivity in humans?
Short-term exposure to repetitive hypoxic apnoeas resets the baroreflex stimulus-response curve to higher blood pressures without altering baroreflex sensitivity, providing insight into autonomic dysregulation in sleep apnea.
Monahan et al. (2006) studied this question.
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