Why the study?
Does combination drug therapy improve management in hypertensive patients?
Does combination drug therapy improve management in hypertensive patients?
Combination drug therapy offers advantages in the management of hypertension, supporting its use as initial therapy in many patients.
May support initial combination therapy in hypertension; extends JNC recommendations but leaves definitive RCTs open.
Combination drug therapy in the management of hypertension has been used for many years. Recent recommendations of the Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and the results of several new multiple-drug trials have focused on using the approach as initial therapy in many hypertensive patients. Results of these long-term outcome trials, as well as short-term and smaller studies, indicate the advantage of multiple-drug therapy in the management of hypertension.
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Marvin Moser (2003) studied this question.
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