Why the study?
Does combination antihypertensive therapy improve blood pressure response in patients who failed single-drug therapy?
Population
102 patients with stage 1 to 2 hypertension who failed to achieve goal blood pressure after treatment with…
Comparison
Combination of the two antihypertensive drugs on… vs Prior single-drug therapy (self-control)
Design
Cohort
Authors
Loading...
May inform sequential antihypertensive choices after monotherapy failure; leaves open optimal order effects pending randomized confirmation.
Does combination antihypertensive therapy improve blood pressure response in patients who failed single-drug therapy?
Combination antihypertensive therapy is highly effective in patients who fail to achieve goal blood pressure on monotherapy, with the order of drug administration potentially influencing the response.
B MATERSON (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: