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October 22, 2019Catheterization and Cardiovascular Interventions

Identification of patients at higher risk for myocardial injury following elective coronary artery intervention

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Why the study?

High-sensitivity troponin assays detect minor cardiac troponin levels, which may help monitor myocardial injury and infarction following elective PCI and guide therapies.

Population

530 patients undergoing elective PCI

Comparison

Extent of CAD by SYNTAX score categories and ACC/AHA lesion classifications

Design

Cohort study

Authors

HSHaitham Abu ShararHeidelberg UniversitySHStefanie HelfertHeidelberg UniversityMVMehrshad VafaieHeidelberg University

Discussion

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Implication

hsTnT rise after elective PCI may reflect CAD complexity; hypothesis-generating and should not yet change practice.

Structured PICO

P
Population
530 patients undergoing elective percutaneous coronary intervention (PCI)
I
Intervention
Serial high-sensitivity troponin T (hsTnT) measurements
O
Outcome
Postprocedural hsTnT increases and rates of myocardial injury and infarction (MI type 4a)surrogate

Postprocedural high-sensitivity troponin T increases following elective PCI correlate significantly with coronary lesion complexity and overall CAD burden.

Cite This Study

Sharar et al. (2019) studied this question.

synapsesocial.com/papers/6a19948760e90a7f5fea6beahttps://doi.org/10.1002/ccd.28549

Topics

Percutaneous coronary interventionCoronary artery disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Significance of Periprocedural Myonecrosis on Outcomes After Percutaneous Coronary Intervention2008 · 177 citations
  2. 2Frequency, causes, predictors, and clinical significance of peri-procedural myocardial infarction following percutaneous coronary intervention2013 · 166 citations
  3. 3Why all the struggle about CK-MB and PCI?2012 · 39 citations
  4. 4Minor Myocardial Damage and Prognosis2002 · 168 citations
  5. 5Analytical Validation of a High-Sensitivity Cardiac Troponin T Assay2009 · 1,088 citations