Why the study?
Does surgical repair improve survival in patients with postinfarction ventricular septal rupture compared to medical management?
Does surgical repair improve survival in patients with postinfarction ventricular septal rupture compared to medical management?
Surgical intervention for postinfarction ventricular septal rupture is associated with long-term survival, whereas medical management is uniformly fatal, with preoperative cardiogenic shock being a major determinant of perioperative mortality.
Authors
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May support surgery in selected postinfarction VSR patients without shock; leaves open need for randomized trials.
Radford et al. (1981) studied this question.
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