Why the study?
Does chronic cigarette smoking increase arterial stiffness in Korean adults?
Does chronic cigarette smoking increase arterial stiffness in Korean adults?
Chronic cigarette smoking is associated with increased central arterial stiffness, as measured by heart-femoral pulse wave velocity, independent of other cardiovascular risk factors.
Smoking was associated with greater central arterial stiffness in Korean adults; leaves open causality and effects of cessation.
Background: Cigarette smoking is an important modifiable cardiovascular risk factor, which is known to acutely increase arterial stiffness. But the chronic effects of smoking on arterial stiffness are still controvertial. We studied the effects of chronic cigarette smoking on arterial stiffness in Korean subjects. Methods: Our subjects included those >18 years of age (n=2685, 991 females) who had undergone a pulse wave velocity from July 2004 to June 2008. They were classified into two groups, smokers (n=641) and non-smokers (n=2044). In addition to the pulse wave velocity (PWV), we reviewed the highly sensitive C-reactive protein levels in a random manner when it was available. Results: Males were predominant in the smokers group. Smokers had significantly higher heart-femoral PWVs than nonsmokers (1083.6264.1 cm/sec vs. 1041.3257.3 cm/sec; p<0.001). There was no linear relationship between smoking duration and PWV (r= -0.225, p=0.506) even after adjusting for age, sex, and body mass index. Furthermore, there was no difference in the ankle-brachial index between the two groups. On the multivariate regression analysis, age, male gender, hypertension, and diabetes were independent predictors of increased arterial stiffness.
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Kim et al. (2011) studied this question.
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