Why the study?
Does propofol compared to thiopental affect seizure duration, stimulus charge, clinical effect, and cognitive side effects in depressed patients undergoing electroconvulsive therapy?
Population
62 depressed patients treated with bilateral ECT
Comparison
Propofol as anesthetic agent vs Thiopental as anesthetic agent
Design
RCT, Randomized, Blinded
Authors
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Propofol shortens seizures and raises charge needs versus thiopental in ECT; extends RCT evidence on anesthetic choice for seizure adequacy.
Does propofol compared to thiopental affect seizure duration, stimulus charge, clinical effect, and cognitive side effects in depressed patients undergoing electroconvulsive therapy?
Propofol decreases seizure duration and requires higher electrical charge compared to thiopental during ECT, potentially leading to more severe cognitive side effects.
Bauer et al. (2009) studied this question.
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