This historical article discusses the recognition of premonitory symptoms in acute myocardial infarction and the potential role of simplified heparin therapy.
Prompt attention to premonitory symptoms may shorten AMI delays; extends early RCT support for simplified heparin.
Article1 March 1956SIMPLIFIED HEPARIN THERAPY OF IMPENDING AND ACUTE MYOCARDIAL INFARCTIONHYMAN ENGELBERG, M.D.HYMAN ENGELBERG, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-3-466 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is now recognized that premonitory symptoms occur in a substantial proportion of all attacks of acute myocardial infarction.1There is a definite change in the clinical picture, with increasingly severe angina and rapidly decreasing effort tolerance. The electrocardiogram at rest may or may not indicate coronary insufficiency, and it is not as important as the clinical story in the diagnosis. This is particularly true when the patient has been under the physician's care for a considerable time. Nevertheless, the diagnosis of impending coronary occlusion cannot be established with absolute certainty unless an infarction actually occurs. 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RussekZohman HIBL: Anticoagulant therapy in acute myocardial infarction. A survey of specialists' opinions concerning indications, results and dangers, Am. J. M. Sc. 225: 813 (June) 1953. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Beverly Hills, California*Received for publication May 13, 1955. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byComparison of continuous long-term heparin and oral anticoagulant therapy in patients with severe angina pectorisThe Use of Anticoagulants in Coronary Heart DiseaseDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktLa période prémonitoire et la période finale de l'infarctus du myocardeChest Pain with Inverted T Waves, Predominantly in Precordial Leads, as the Only Electrocardiographic AbnormalityCardiac EmergenciesTHE FAILURE OF ANTICOAGULANT THERAPY TO PREVENT MYOCARDIAL INFARCTION IN PATIENTS WITH PREMONITORY SYMPTOMS OF AN IMPENDING CORONARY OCCLUSION*MILTON SCHLACHMAN, M.D., F.A.C.P.Anticoagulant therapy in coronary artery disease 1 March 1956Volume 44, Issue 3Page: 466-475KeywordsAnticoagulantsAttentionEdemaElectrocardiographyHemorrhageHeparinHyperlipidemiaInfarctionLaboratory testsMyocardial infarction ePublished: 1 December 2008 Issue Published: 1 March 1956 PDF downloadLoading ...
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Hyman Engelberg (1956) studied this question.
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