Why the study?
Electroporation has potential for permanent pulmonary vein isolation and selective efficacy on cardiac tissue, but strong evidence of selective myocardial injury is lacking.
Does electroporation selectively induce cell death in cardiomyocytes compared to neurons and smooth muscle cells in vitro?
Does electroporation selectively induce cell death in cardiomyocytes compared to neurons and smooth muscle cells in vitro?
In vitro electroporation demonstrates selective cytotoxicity for cardiomyocytes over neurons and smooth muscle cells, supporting its potential safety profile for pulmonary vein isolation.
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Hunter et al. (2021) studied this question.
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