Does the Naples prognostic score (NPS) predict long-term mortality in patients with heart failure?
The Naples prognostic score, which incorporates albumin, total cholesterol, NLR, and LMR, shows promise as an independent predictor of long-term mortality in heart failure patients.
BACKGROUND: Heart failure (HF) remains a significant health problem despite advances in diagnosis and treatment options. Malnutrition and increased inflammation predict poor disease prognosis. The parameters of the Naples prognostic score (NPS) include albumin, total cholesterol, neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR). We aimed to assess the potential of NPS as a predictor of long-term mortality in patients with HF. METHODS: A total of 1728 patients with HF who applied to our center between 2018 and 2022 were included in this study. The NPS was computed and the patients were divided into three groups according to their NPS values as follows: NPS = 0 (Group 1), NPS = 1-2 (Group 2), and NPS = 3-4 (Group 3). We also evaluated the association between NPS value and HF mortality. RESULTS: = 0.014). According to the Kaplan-Meier plot and log-rank analyses, there was a statistically significant difference in the long-term mortality of patients with HF and their NPS values for the entire cohort. CONCLUSION: Based on our findings, NPS showed promise as an independent predictor of long-term mortality in individuals with HF.
Aydın et al. (Sat,) studied this question.