Why the study?
Does chronic infusion of a low dose of angiotensin II increase mean arterial pressure in conscious sheep?
Does chronic infusion of a low dose of angiotensin II increase mean arterial pressure in conscious sheep?
Chronic infusion of a subpressor dose of angiotensin II induces hypertension via generalized peripheral vasoconstriction, without apparent involvement of central angiotensinergic mechanisms or fluid retention.
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Supports ANG II pressor effects in sheep models; leaves open human translation and mechanisms.
Hood et al. (2007) studied this question.
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