What does this research mean for the field?

A newly developed 44-item self-administered carotenoid intake screener demonstrates acceptable relative validity for assessing total carotenoid intake in nonobese adults, correlating significantly with both plasma and skin carotenoid concentrations. Novelty: ClaimNovelty.METHODOLOGICAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the relative validity of a newly developed 44-item carotenoid intake screener against circulating plasma and skin carotenoid biomarkers in nonobese adults.

December 23, 2022Current Developments in NutritionOpen Access

Biochemical Validation of a Self-Administered Carotenoid Intake Screener to Assess Carotenoid Intake in Nonobese Adults

View Full Paper

Ask AI

Bookmark

Why the study?

Detailed food frequency questionnaires impose a high participant burden with marginal accuracy gains, creating a need for a brief validated carotenoid intake screener.

Does a 44-item carotenoid intake screener accurately assess carotenoid intake compared to plasma and skin carotenoid concentrations in healthy nonobese adults?

Population

83 healthy nonobese Midwestern American adults aged 18-65 y

Comparison

44-item carotenoid screener vs plasma and skin carotenoid concentrations

Design

Secondary validation analysis of a parent study

Follow-up

8-wk

Authors

SCShanon CaspersonAgricultural Research Service ASAngela ScheettUniversity of North Dakota DPDaniel G. PalmerAgricultural Research Service

Discussion

Member takes

Implication

Supports screener use in observational research; leaves open clinical adoption pending further validation.

Key Points

To evaluate the relative validity of a newly developed 44-item carotenoid intake screener against circulating plasma and skin carotenoid biomarkers in nonobese adults.
Conducted a secondary analysis of an 8-week parent trial (The Juice Study, NCT03202043) in 83 healthy adults aged 18–65 years with a BMI of 18.5–29.9 kg/m2.
Participants completed the 44-item screener weekly; plasma carotenoids were measured at weeks 0, 4, and 8 using HPLC, and skin carotenoids were measured weekly using pressure-mediated reflection spectroscopy.
Mixed-model correlation matrices evaluated the longitudinal associations between self-reported intake and biomarker concentrations.
Total carotenoid intake from the screener significantly correlated with both plasma total carotenoid concentrations (r = 0.52; P < 0.0001) and reflection spectroscopy-assessed skin carotenoids (r = 0.43; P < 0.0001).
Significant correlations between reported intake and plasma concentrations were observed for individual carotenoids, including α-carotene (r = 0.40; P = 0.0002), lycopene (r = 0.33; P = 0.0022), and cryptoxanthin (r = 0.28; P = 0.0113).

Structured PICO

Does a 44-item carotenoid intake screener accurately assess carotenoid intake compared to plasma and skin carotenoid concentrations in healthy nonobese adults?

Population

Healthy adults (n = 83; 25 men and 58 women) aged 18–65 y (mean age, 32 ± 12 y) with a BMI of 18.5–29.9 (mean BMI, 25 ± 3) in Midwestern America.

Intervention

44-item carotenoid intake screener completed weekly over 8 weeks

Outcome

Plasma carotenoid concentrations assessed at weeks 0, 4, and 8 using HPLCsurrogate

A 44-item carotenoid intake screener demonstrates acceptable relative validity for assessing total carotenoid intake in healthy adults with normal weight or overweight.

Cite This Study

Casperson et al. (2022) studied this question.

synapsesocial.com/papers/6a19b64fa2165c1276deef5f https://doi.org/10.1016/j.cdnut.2022.100024

View Full Paper

Ask AI

Bookmark