Why the study?
Does polycystic ovary syndrome (an insulin-resistant state) increase arterial blood pressure or left ventricular mass in women compared to normal controls?
Population
32 women
Comparison
Polycystic ovary syndrome / insulin-resistant… vs Normal control women
Design
Case-control
Authors
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Similar ambulatory BP and LVM in PCOS vs controls; challenges insulin resistance–hypertension hypothesis but hypothesis-generating and requires prospective confirmation.
Does polycystic ovary syndrome (an insulin-resistant state) increase arterial blood pressure or left ventricular mass in women compared to normal controls?
Despite profound insulin resistance and hyperinsulinemia, women with polycystic ovary syndrome do not exhibit increased arterial blood pressure or left ventricular mass compared to matched controls.
Zimmermann et al. (1992) studied this question.