Key result
Singular spectrum analysis revealed that patients with atrial fibrillation recurrence after ablation had significantly higher left atrium dominant frequencies compared to those who maintained sinus rhythm.
Why the study?
The success of pulmonary vein ablation for AF in restoring normal sinus rhythm is limited in part by uncertainty in the mechanisms that sustain AF.
Does dominant frequency calculated by singular spectrum analysis predict atrial fibrillation recurrence after ablation in patients with AF?
Observational (n=43)
No
Does dominant frequency calculated by singular spectrum analysis predict atrial fibrillation recurrence after ablation in patients with AF?
Absolute Event Rate: 6.61% vs 5.49%
p-value: p=0.02
Singular spectrum analysis of intra-atrial recordings can calculate dominant frequencies that may help predict atrial fibrillation recurrence after ablation.
Higher dominant frequencies may predict post-ablation AF recurrence; hypothesis-generating and requires prospective validation before clinical use.
The goal of pulmonary vein ablation for atrial fibrillation (AF) is returning to normal sinus rhythm; nevertheless it success is limited in part by uncertainly in the mechanisms that sustain AF. 43 AF patients were submitted to an ablation procedure and monitored after ablation. Dominant frequency from intra-atrial recordings obtained before the intervention were analysed in order to predict AF recurrence. The novelty of this study is that dominant frequency was calculated from reconstructed signal by singular spectrum analysis (SSA) application. Patients that maintained sinus rhythm and patients with recurrence in AF showed differences in left atrium dominant frequencies, with higher values in the recurrent AF group than in group without recurrence in the arrhythmia (p=0.02). Moreover, differences between both atria were found in the non-recurrent group, with 5.76 1.31 Hz in the left atrium vs. 6.251.23 Hz in the right atrium (p=0.03). These findings show the potential of SSA as a preprocessing method and results are congruent with previous studies.
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Cervigón et al. (2018) conducted an observational in Atrial fibrillation (n=43). Singular Spectrum Analysis (SSA) of dominant frequency vs. Non-recurrent AF patients was evaluated on Left atrium dominant frequency (Hz) (p=0.02). Singular spectrum analysis revealed that patients with atrial fibrillation recurrence after ablation had significantly higher left atrium dominant frequencies compared to those who maintained sinus rhythm.
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